Phenotype of vitamin D receptor gene polymorphisms, impact of feeding flaxseed oil, and osteoporosis in ovariectomised diabetic rats
The study included rats were classified in groups as control, diabetic, diabetic received flaxseed oil in the diet, ovariectomised (ovx), and ovx-diabetic received flaxseed oil in the diet. Insulin growth factor-1 (IGF-1) urinary deoxypyridinoline (DPD), and osteocalcin were increased (1.470 ± 88.1)...
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| Định dạng: | BB |
| Ngôn ngữ: | English |
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2021
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| Truy cập trực tuyến: | http://tailieuso.tlu.edu.vn/handle/DHTL/10539 |
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oai:localhost:DHTL-105392021-03-17T09:03:27Z Phenotype of vitamin D receptor gene polymorphisms, impact of feeding flaxseed oil, and osteoporosis in ovariectomised diabetic rats El-Saeed, G.S. M. Elghoroury, E.A. Morsy, S. Aly, H.M. Wafaey, H. Osteoporosis Diabetes Flaxseed oil Vitamin D receptor gene Polymorphisms The study included rats were classified in groups as control, diabetic, diabetic received flaxseed oil in the diet, ovariectomised (ovx), and ovx-diabetic received flaxseed oil in the diet. Insulin growth factor-1 (IGF-1) urinary deoxypyridinoline (DPD), and osteocalcin were increased (1.470 ± 88.1), (160 ± 7.11), (21.25 ± 2.33) respectively in ovx. and have significantly positive correlation (p < 0.05): their lowest levels were detected. Upon adding flaxseed oil. Bone mineral density (BMD) and content (BMC) were reduced (0.061 ± 0.0046), (0.041 ± .0048) in all groups and increased (0.070 ± 0.0046), (0.063 ± 0.0045) upon adding flaxseed oil which have a ratio of 13.90 ± 0.01:21.10 ± 0.40 and there is correlation between bone marker and gene polymorphism after receiving flaxseed oil. https://bnrc.springeropen.com/articles/10.1186/s42269-018-0003-8 2021-03-17T09:03:27Z 2021-03-17T09:03:27Z 2018 BB 2522-8307 http://tailieuso.tlu.edu.vn/handle/DHTL/10539 en Bulletin of the National Research Centre, Vol 42:11 (2018) |
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Trường Đại học Thủy Lợi |
| collection |
DSpace |
| language |
English |
| topic |
Osteoporosis Diabetes Flaxseed oil Vitamin D receptor gene Polymorphisms |
| spellingShingle |
Osteoporosis Diabetes Flaxseed oil Vitamin D receptor gene Polymorphisms El-Saeed, G.S. M. Phenotype of vitamin D receptor gene polymorphisms, impact of feeding flaxseed oil, and osteoporosis in ovariectomised diabetic rats |
| description |
The study included rats were classified in groups as control, diabetic, diabetic received flaxseed oil in the diet, ovariectomised (ovx), and ovx-diabetic received flaxseed oil in the diet. Insulin growth factor-1 (IGF-1) urinary deoxypyridinoline (DPD), and osteocalcin were increased (1.470 ± 88.1), (160 ± 7.11), (21.25 ± 2.33) respectively in ovx. and have significantly positive correlation (p < 0.05): their lowest levels were detected. Upon adding flaxseed oil. Bone mineral density (BMD) and content (BMC) were reduced (0.061 ± 0.0046), (0.041 ± .0048) in all groups and increased (0.070 ± 0.0046), (0.063 ± 0.0045) upon adding flaxseed oil which have a ratio of 13.90 ± 0.01:21.10 ± 0.40 and there is correlation between bone marker and gene polymorphism after receiving flaxseed oil. |
| author2 |
Elghoroury, E.A. |
| author_facet |
Elghoroury, E.A. El-Saeed, G.S. M. |
| format |
BB |
| author |
El-Saeed, G.S. M. |
| author_sort |
El-Saeed, G.S. M. |
| title |
Phenotype of vitamin D receptor gene polymorphisms, impact of feeding flaxseed oil, and osteoporosis in ovariectomised diabetic rats |
| title_short |
Phenotype of vitamin D receptor gene polymorphisms, impact of feeding flaxseed oil, and osteoporosis in ovariectomised diabetic rats |
| title_full |
Phenotype of vitamin D receptor gene polymorphisms, impact of feeding flaxseed oil, and osteoporosis in ovariectomised diabetic rats |
| title_fullStr |
Phenotype of vitamin D receptor gene polymorphisms, impact of feeding flaxseed oil, and osteoporosis in ovariectomised diabetic rats |
| title_full_unstemmed |
Phenotype of vitamin D receptor gene polymorphisms, impact of feeding flaxseed oil, and osteoporosis in ovariectomised diabetic rats |
| title_sort |
phenotype of vitamin d receptor gene polymorphisms, impact of feeding flaxseed oil, and osteoporosis in ovariectomised diabetic rats |
| publishDate |
2021 |
| url |
http://tailieuso.tlu.edu.vn/handle/DHTL/10539 |
| work_keys_str_mv |
AT elsaeedgsm phenotypeofvitamindreceptorgenepolymorphismsimpactoffeedingflaxseedoilandosteoporosisinovariectomiseddiabeticrats |
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