Flaxseed oil as a protective agent against bisphenol-A deleterious effects in male mice
The results showed that BPA induced a significant raise in DNA damage that obviously appear in the increase of tail length, tail DNA percentage, and tail moment in the liver and testes. In addition, there was an increase in the frequency of micronuclei in bone marrow cells. Liver and testes histopat...
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| Định dạng: | BB |
| Ngôn ngữ: | English |
| Thông tin xuất bản: |
2021
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| Chủ đề: | |
| Truy cập trực tuyến: | http://tailieuso.tlu.edu.vn/handle/DHTL/10533 |
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| Tóm tắt: | The results showed that BPA induced a significant raise in DNA damage that obviously appear in the increase of tail length, tail DNA percentage, and tail moment in the liver and testes. In addition, there was an increase in the frequency of micronuclei in bone marrow cells. Liver and testes histopathological alterations and sperm count and motility significant comedown were seen in male mice exposed to BPA as well. Conversely, flaxseed oil oral administration through the three regimens of treatment effectively attenuated the abovementioned effects. Moreover, administration of flaxseed oil before BPA treatment was the best protocol in the attenuation of BPA toxic effects. |
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