Nghiên cứu khả năng kháng oxy hóa và ức chế Enzym α-Glucosidase của cao chiết từ lá cây lá Đắng (Vernonia amygdalina Del.), họ Cúc (Asteraceae) / Nguyễn Thị Chi, Phạm Việt Trang, Lê Xuân Tiến, Nguyễn Văn Thanh
The plant Vernonia amygdalina Del. (Asteraceae) (“lá đắng” - bitter leaf plant) was studied for antioxidant activity and inhibitive power on α-glucosidase enzyme. The dichloromethane extracts showed the best in bioactivities in question. The extraction was investigated for high efficiency and poten...
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Phạm, Việt Trang
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| Truy cập trực tuyến: | http://elib.ntt.edu.vn/Opac/DmdInfo.aspx?dmd_id=18717 |
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| Tóm tắt: | The plant Vernonia amygdalina Del. (Asteraceae) (“lá đắng” - bitter leaf plant) was studied for antioxidant activity and inhibitive power on α-glucosidase enzyme. The dichloromethane extracts showed the best in bioactivities in question. The extraction was investigated for high efficiency and potential inhibitivity on α-glucosidase enzyme. Finally, the extration was optimized as: the plant powders were extracted three times, once with ethanol 40% (v/v), solid-to-liquid ratio of 1/5 (w/v) at 50oC for 40 min. The obtained extracts showed antioxidant activity (IC50 = 51.9 μg/mL) and good inhibitivity on α-glucosidase enzyme (IC50 = 480 μg/mL), much higher than the ethanol and aqueous extracts.
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