Single particle detection in CMOS compatible photonic crystal nanobeam cavities

We report the label-free detection of single particles using photonic crystal nanobeam cavities fabricated in silicon-on-insulator platform, and embedded inside microfluidic channels fabricated in poly - dimethylsiloxane (PDMS). Our system operates in the telecommunication wavelength band, thus leve...

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Tác giả chính: Quan, Qimin, Floyd, Daniel L., Burgess, Ian B., Deotare, Parag B., Frank, Ian W., Tang, Sindy K. Y., Ilic, Rob, Loncar, Marko
Định dạng: Journal Article
Ngôn ngữ:en_US
Thông tin xuất bản: Optical Society of America 2019
Truy cập trực tuyến:http://nrs.harvard.edu/urn-3:HUL.InstRepos:41461263
https://lib.cdythadong.edu.vn/handle/HDMC/28003
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spelling CDYTHD-HDMC-280032024-12-03T15:09:47Z Single particle detection in CMOS compatible photonic crystal nanobeam cavities Quan, Qimin Floyd, Daniel L. Burgess, Ian B. Deotare, Parag B. Frank, Ian W. Tang, Sindy K. Y. Ilic, Rob Loncar, Marko We report the label-free detection of single particles using photonic crystal nanobeam cavities fabricated in silicon-on-insulator platform, and embedded inside microfluidic channels fabricated in poly - dimethylsiloxane (PDMS). Our system operates in the telecommunication wavelength band, thus leveraging the widely available, robust and tunable telecom laser sources. Using this approach, we demonstrated the detection of polystyrene nanoparticles with dimensions down to 12.5nm in radius. Furthermore, binding events of a single streptavidin molecule have been observed. Version of Record 2019-10-03T14:39:21Z 2013 2019-10-03T14:39:21Z 2023-04-10T07:42:00Z 2024-12-03T08:09:47Z 2023-04-10T07:42:00Z 2024-12-03T08:09:47Z Journal Article Quan, Qimin, Daniel L. Floyd, Ian B. Burgess, Parag B. Deotare, Ian W. Frank, Sindy K. Y. Tang, Rob Ilic, and Marko Loncar. 2013. “Single Particle Detection in CMOS Compatible Photonic Crystal Nanobeam Cavities.” Optics Express 21 (26): 32225. https://doi.org/10.1364/oe.21.032225. 1094-4087 http://nrs.harvard.edu/urn-3:HUL.InstRepos:41461263 10.1364/OE.21.032225 https://lib.cdythadong.edu.vn/handle/HDMC/28003 en_US Optics Express application/pdf application/pdf 70306 oe-21-26-32225.pdf Optical Society of America https://lib.cdythadong.edu.vn/handle/HDMC/28003
institution Trường Cao đẳng Y tế Hà Đông
collection DSpace
language en_US
description We report the label-free detection of single particles using photonic crystal nanobeam cavities fabricated in silicon-on-insulator platform, and embedded inside microfluidic channels fabricated in poly - dimethylsiloxane (PDMS). Our system operates in the telecommunication wavelength band, thus leveraging the widely available, robust and tunable telecom laser sources. Using this approach, we demonstrated the detection of polystyrene nanoparticles with dimensions down to 12.5nm in radius. Furthermore, binding events of a single streptavidin molecule have been observed.
format Journal Article
author Quan, Qimin
Floyd, Daniel L.
Burgess, Ian B.
Deotare, Parag B.
Frank, Ian W.
Tang, Sindy K. Y.
Ilic, Rob
Loncar, Marko
spellingShingle Quan, Qimin
Floyd, Daniel L.
Burgess, Ian B.
Deotare, Parag B.
Frank, Ian W.
Tang, Sindy K. Y.
Ilic, Rob
Loncar, Marko
Single particle detection in CMOS compatible photonic crystal nanobeam cavities
author_facet Quan, Qimin
Floyd, Daniel L.
Burgess, Ian B.
Deotare, Parag B.
Frank, Ian W.
Tang, Sindy K. Y.
Ilic, Rob
Loncar, Marko
author_sort Quan, Qimin
title Single particle detection in CMOS compatible photonic crystal nanobeam cavities
title_short Single particle detection in CMOS compatible photonic crystal nanobeam cavities
title_full Single particle detection in CMOS compatible photonic crystal nanobeam cavities
title_fullStr Single particle detection in CMOS compatible photonic crystal nanobeam cavities
title_full_unstemmed Single particle detection in CMOS compatible photonic crystal nanobeam cavities
title_sort single particle detection in cmos compatible photonic crystal nanobeam cavities
publisher Optical Society of America
publishDate 2019
url http://nrs.harvard.edu/urn-3:HUL.InstRepos:41461263
https://lib.cdythadong.edu.vn/handle/HDMC/28003
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